PHPMailer,php.ini配置

I was trying to find what i should change on php.ini settings to allow PHPMailer to work, Is there any guide that explain what i should change on php.ini?, Thank you all and have a nice day.

or you can relay GMAIL if you don't have any email server. http://www.icpep.org/use-gmail-account-to-relay-email-from-php-mail-function/