参数化插入

I am trying to insert values in table1 if it does not exist on table2. While I can do that using the following:

INSERT INTO table1 (start, stop)
SELECT    a.*
FROM      (SELECT 123456789 start, 234567890 stop) a
LEFT JOIN table2 b ON (a.start,a.stop) IN ((b.start,b.stop))
WHERE     b.start IS NULL

You can see the example here https://stackoverflow.com/a/11998641/719554

I would like to parametrize 123456789 and 234567890 using PDO. HOw can I accomplish that? I thought that I could simply do the following

INSERT INTO table1 (start, stop)
SELECT    a.*
FROM      (SELECT :start AS start, :stop AS stop) a
LEFT JOIN table2 b ON (a.start,a.stop) IN ((b.start,b.stop))
WHERE     b.start IS NULL