具有多个条件的SQL更新

I know this is quite simple but I've been looking at this for awhile and can't seem to identify what the issue is. I want to update a row in a table using two criteria. When I use either criteria, the table updates fine but when I combine them, it doesn't work.

This is the query

$updatequery = "UPDATE query SET audio='$finalpath' WHERE content='$title' AND WHERE userid LIKE '%$regID%'";

An example of the reg id:

APA91bGHS59rrpM0sbX9PIYT3SzXs-W1yEtGa2xGMGJXi8O1vW2SrgN7koHDj2o6ZwKvkd3TxtzhktsiVtQNSYQRa4uNDF7Yy0VOf0BJfQOnJWMtN2WBQjmVDsuU-0GxmceNLd8SWqOM

An example of content : Where can I find a car

WHERE content='$title' AND userid LIKE '%$regID%'

Where is needed only once

You only need to use the where keyword once:

$updatequery = 
"UPDATE query SET audio='$finalpath' WHERE content='$title' AND userid LIKE '%$regID%'";
# "WHERE" removed here ------------------------------------^

Mandatory comment:
Using string manipulation like this leaves your code vulnerable to SQL-injection attacks. You should really consider using prepared statements instead.

Your query is wrong.

Try this:

 $updatequery = "UPDATE query SET audio='$finalpath' WHERE content='$title' AND userid LIKE '%$regID%'";

EDIT: Where is needed only once.

You can have only one WHERE clause, so this is a syntax error:

WHERE content='$title' AND WHERE userid LIKE '%$regID%'

Combine the logic in a single clause:

WHERE content='$title' AND userid LIKE '%$regID%'

The WHERE clause essentially works like conditionals in any other language. You can build up as complex a tree of boolean conditions as you like, as long as the whole thing resolves down to a boolean then it's fine.