R 错误: 没有".libPath"这个函数 停止执行

打开R就显示 Error: could not find function ".libPath"

运行以下代码

> BiocManager::install("org.Hs.eg.db")

'getOption("repos")' replaces Bioconductor standard repositories, see '?repositories' for
details

replacement repositories:
    CRAN: https://mirrors.tuna.tsinghua.edu.cn/CRAN/

Bioconductor version 3.14 (BiocManager 1.30.16), R 4.1.3 (2022-03-10)
Installing package(s) 'org.Hs.eg.db'
安装源码包‘org.Hs.eg.db’

trying URL 'https://bioconductor.org/packages/3.14/data/annotation/src/contrib/org.Hs.eg.db_3.14.0.tar.gz'
Content type 'application/x-gzip' length 82195112 bytes (78.4 MB)
downloaded 624 KB

错误: 没有".libPath"这个函数
停止执行

Warning messages:
1: In .inet_warning(msg) : lzma decoding result 10
2: In .inet_warning(msg) :
  downloaded length 638976 != reported length 82195112
3: In .inet_warning(msg) :
  installation of package ‘org.Hs.eg.db’ had non-zero exit status

手动下载R包安装

> install.packages("C：/.../downloaded_packages/org.Hs.eg.db_3.14.0.tar.gz", repos = NULL, type = "source")
错误: 没有".libPath"这个函数
停止执行
Warning in install.packages :
  installation of package ‘C:/.../downloaded_packages/org.Hs.eg.db_3.14.0.tar.gz’ had non-zero exit status

晴天霹雳，??.libPath也没找到函数的归属，这该怎么办啊