An unknown server-side error occurred while processing the command. Original error: zipAlignApk failed. Original error: Unable to open 'C:\Users\Administrator\AppData\Local\Programs\Appium\resources\app\node_modules\appium\node_modules\appium-uiautomator2-server\apks\appium-uiautomator2-server-debug-androidTest.apk' as zip archive
在github上有解决建议方案是将文件夹
C:\Users\xxx\AppData\Roaming\npm\node_modules\appium\node_modules\appium-uiautomator2-server\apks
设置为可读写权限，你可尝试一下，参考：
https://github.com/appium/appium/issues/12355