android studio启动genymotion失败

前几天还能正常启动，然后今天就初始化失败了，然后看了网上也不是没有reg.exe文件，请各位大神帮帮忙吧

9:21:03 Genymotion: Loading Genymotion library
9:21:03 Genymotion: Genymotion directory: E:\workSoftware\genymotion2.5.3\Genymotion
9:21:03 Genymotion: Trying to initialize engine
9:21:04 Genymotion: vboxPath: C:\Program Files\Oracle VM VirtualBox\VBoxManage.exe
9:21:04 Genymotion: Launch process: C:\Program Files\Oracle VM VirtualBox\VBoxManage.exe --version
9:21:04 Genymotion: Exception (C:\Program Files\Oracle VM VirtualBox\VBoxManage.exe)
9:21:04 Genymotion: Initialize Engine: failed

然后我又尝试使用android studio自带的模拟器，提示

这又是什么原因啊！！！！

还能正常启动，然后今天就初始化失败了，然后看了网上也不是没有reg.exe文件，请各位大神帮帮忙吧
9:21:03 Genymotion: Loading Genymotion library
9:21:03 Genymotion: Genymotion directory: E:\workSoftware\genymotion2.5.3\Genymotion
9:21:03 Genymotion: Trying to initialize engine
9:21:04 Genymotion: vboxPath: C:\Program Files\Oracle VM VirtualBox\VBoxManage.exe
9:21:04 Genymotion: Launch process: C:\Program Files\Oracle VM VirtualBox\VBoxManage.exe --version
9:21:04 Genymotion: Exception (C:\Program Files\Oracle VM VirtualBox\VBoxManage.exe)
9:21:04 Genymotion: Initialize Engine: fa