WMI之类的我已经试过了，用不成。
但有使用C#，调用openhardwaremonitorlib.dll库文件 成功案例。
现有需求要在VB 6 编程环境下，使用openhardwaremonitorlib.dll库文件 ，
解决实时读取CPU和硬盘温度的需求。

wmi其实也是可以的，只是一些主板硬件不支持，另外你既然提到openhardwaremonitorlib.dll，其实你可以用regasm可以把它暴露成com接口，然后vb6以activex dll的方式饮用后可以调用。

帮你搞了一个
看下面的效果：

Private Sub Command1_Click()
    Dim obj As Object
    Set obj = CreateObject("Q1093036Lib.Class1")
    Dim s As String
    s = obj.GetTemperature()
    MsgBox s
End Sub

using System;
using System.Collections.Generic;
using System.Linq;
using System.Text;
using OpenHardwareMonitor;
using OpenHardwareMonitor.Collections;
using OpenHardwareMonitor.Hardware;
using System.Runtime.InteropServices;

namespace Q1093036Lib
{
    [ComVisible(true)]
    public class Class1
    {
        [ComVisible(true)]
        public string GetTemperature()
        {
            string s = "";
            Computer computer = new Computer();
            computer.MainboardEnabled = true;
            computer.CPUEnabled = true;
            computer.HDDEnabled = true;
            computer.RAMEnabled = true;
            computer.GPUEnabled = true;
            computer.FanControllerEnabled = true;
            computer.Open();

            foreach (var hardware in computer.Hardware)
            {
                hardware.Update();
                foreach (var sensor in hardware.Sensors)
                {
                    s += sensor.Name + ":" + sensor.Value + "\r\n";
                }
            }
            return s;
        } 
    }
}

留下email，采纳回答，把完整的项目代码给你

其他人如果也需要，可以从 https://download.csdn.net/download/caozhy/12683629 下载

https://blog.csdn.net/xjnzhidao/article/details/48105717
https://stackoverflow.com/questions/1404731/how-to-get-current-cpu-and-ram-usage-in-vb-6
https://stackoverflow.com/questions/31774626/how-can-i-see-temperature-of-cpu-using-vb-net-with-open-hardware-monitor-dll